TheraNovis

AstraBCF kit

A next-generation technology enabling simultaneous imaging of proteins and RNA, optimized for drug development and biomarker discovery (Hyperplex IF)

Technical Specifications
AstraBCF kit
Reagents

Overview

AstraBCF is a specially formulated fixative that optimizes the retention of molecular barcodes during tissue processing. It ensures minimal signal loss and maximum readout accuracy for barcode-based assays.

Key Features

  • Barcode optimization
  • Superior preservation
  • Low autofluorescence
  • Easy integration

Key Performance Metrics

* Based on internal test results

Protein + RNA Co-imaging

Simultaneous visualization of proteins and RNA on a single tissue section—enabling next-gen spatial multi-omics

95%+ Barcode Retention

Minimized molecular barcode loss throughout tissue processing maximizes readout accuracy

Minimized Autofluorescence

Special formulation suppresses background noise for clear signals even in 10+ plex panels

Drug Development Optimized

Full Hyperplex IF support tailored for biomarker discovery and drug response evaluation

Strategic Advantage

Discover the overwhelming performance advantages over conventional methods and competitors.

METRICSManualExisting
OUR SOLUTIONAstraBCF kit
Simultaneous Detection
Protein or RNA only (single type)Protein-centric (limited RNA)
Simultaneous protein + RNA imaging
Barcode Retention
50%+ loss during fixation~70% retention
95%+ barcode preservation rate
Autofluorescence
Increased post-fixation autofluorescenceModerate autofluorescence
Minimized autofluorescence formulation
Hyperplex Compatibility
Difficult for high-plex panelsUp to 5–7-plex panels
Full support for 10+ Hyperplex IF
* Verification Data Available Upon Request

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